Finding Novel Targets to Harness Myeloid Repolarization, Demonstrating Functional Change & Anti-Tumor Activity in Preclinical Development

Time: 5:00 pm
day: Day Two


• Defining the term ‘repolarization’ in the context of myeloid cells: recruiting new macrophages vs. changes in tumor-resident macrophages

• Maintaining myeloid cells ex vivo and characterizing the function of M1 vs. M2 phenotypes to determine anti-tumor effects

• Leveraging functional information to identify and validate myeloid targets for clinical development